Endometrial Biopsy

What is an endometrial biopsy?

An endometrial biopsy is a procedure to learn more about your condition by taking a sample of the lining of your uterus. The uterus is a muscular organ at the top of the vagina where menstruation begins and babies grow when you are pregnant. The lining of the uterus is called the endometrium.

When is it used?

This procedure may be performed because the uterus is bleeding too much, at the wrong times, or not at all.

Examples of alternatives to this procedure are:

  • to have a D&C (dilation and curettage, which means stretching the cervix and scraping the inside of the uterus)
  • to have a hysteroscopy (examination of the uterus using a thin telescopelike tube with a light and a tool) to remove part of the endometrium
  • to choose not to have treatment.

You should ask your doctor about these choices.

How do I prepare for an endometrial biopsy?

Follow instructions provided by your doctor. Your doctor may prescribe a mild pain pill to take an hour before doing the biopsy.

What happens during the procedure?

The doctor will gently stretch open your cervix and guide a biopsy instrument into the uterus to remove a sample from the lining of the uterus. The doctor will send the sample to the lab for analysis. You may have mild cramps during the procedure.

What happens after the procedure?

You may leave in a few minutes after the procedure is completed. You may have some cramping and bleeding after the procedure. Mild pain medication should control any discomfort.

Ask your doctor when you can expect to receive the biopsy results. Also ask what steps you should take and when you should come back for a checkup.

What are the benefits of this procedure?

  • It is a simple office procedure that does not require any anesthesia.
  • The doctor may learn more about what is causing your symptoms.